Considering its burden, efficient management of DR patients depends on proper classification and severity grading which, in turn, lay the foundations on the most appropriate imaging modality. Diabetic retinopathy (DR) is a microangiopathic complication of DM and, despite the latest diagnostic and therapeutic advancements, is still one of the leading causes of blindness worldwide, affecting about one-third of diabetic patients. Introductionĭiabetes mellitus (DM) is a major public health concern, with a global prevalence expected to rise from 8.8% in 2015 to 10.4% in 2040. Further studies will facilitate the migration from traditional imaging to WF-OCTA in both the research and clinical practice fields. WF-OCTA harbors interesting potential in DR because of its noninvasiveness and capability of objective metrics of retinal vasculature. Curvature, segmentation, and motion artifacts should be assessed when using WF-OCTA. Quantitative estimates and topographic distribution of NPA and NV are useful for treatment monitoring and artificial intelligence-based approaches. WF-OCTA can be obtained with different approaches, offering advantages over traditional imaging in the study of nonperfusion areas (NPAs) and neovascularization (NV). All studies published in English up to August 2020 were reviewed. A PubMed-based search was carried out using the terms “Diabetic retinopathy”, “optical coherence tomography angiography”, “widefield imaging”, and “ultra-widefield imaging”. To summarize the role of widefield optical coherence tomography angiography (WF-OCTA) in diabetic retinopathy (DR), extending from the acquisition strategies to the main clinical findings. Also, the preoperative and postoperative data acquired will be compared.Purpose. After that, the cerebral and ocular data between the two groups will be compared. This study aims to evaluate ocular changes in patients with carotid artery stenosis by optical coherence tomography angiography before and after carotid artery revascularization procedure.In this study, the patients with carotid artery stenosis and control group will receive a series of cerebral and ocular examinations including the most important cerebral CT perfusion (CTP) and OCTA. Recent studies have also demonstrated the ability of OCTA to quantify retinal microvascular changes in monitoring cardiovascular risk. Optical coherence tomography angiography (OCTA) is a novel, non-invasive imaging modality that can be a reliable tool for the qualitative and quantitative assessments of ocular vessels during various ocular pathological or physiological changes. Since blood flow to the retina is predominantly supplied by the internal carotid artery (ICA), we hypothesized that ocular microvasculature and structure changes may reflect the disease status or therapeutic effects in patients with carotid artery stenosis. Why Should I Register and Submit Results?Ī growing body of research indicates that abnormal ocular microvascular features may serve as a novel biomarker reflecting the severity of underlying cardiovascular, neurodegenerative, and microvascular disease.
0 Comments
Leave a Reply. |